Evaluation of bivalent inactivated oil adjuvant African Horse Sickness vaccine in Guinea pigs and mice

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Inactivated African horse sickness virus cell culture vaccine.

Immunogenic killed vaccine against African Horse Sickness can ce prepared from a neurotropic vaccine strain or a virulent strain of virus, type 9, grown in a monkey kidney stable cell line. Virus was inactiv:ttd with either formaldehyde in a final concentration of 1 :8000 or j3-propiolactone at 0.2 per cent. In order to enhance the immunogenicty of the product, aluminium hydroxide was added to ...

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Evaluation of cytokine mRNA expression in vaccinated guinea pigs with foot-and-mouth disease type O inactivated vaccine

Foot-and-mouth disease (FMD) is a severely contagious viral disease that mainly affects cloven-hoofedlivestock and wildlife. This study quantifies the cytokines mRNA expression of vaccinated guinea pigs withFMD type O inactivated vaccine. Blood samples were collected from eight guinea pigs at 7 and 28 days after thefirst vaccination. Extracted mRNAs were reverse-transcribed into cDNA and analyz...

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ژورنال

عنوان ژورنال: Journal of Veterinary Medical Research

سال: 2008

ISSN: 2357-0520

DOI: 10.21608/jvmr.2008.77845